TRANSGENIC GDNF POSITIVELY INFLUENCES PROLIFERATION, DIFFERENTIATION, MATURATION AND SURVIVAL OF MOTOR NEURONS PRODUCED FROM MOUSE EMBRYONIC STEM CELLS.

TRANSGENIC GDNF POSITIVELY INFLUENCES PROLIFERATION, DIFFERENTIATION, MATURATION AND SURVIVAL OF MOTOR NEURONS PRODUCED FROM MOUSE EMBRYONIC STEM CELLS.

Embryonic stem cells (ESC) are pluripotent and thus can differentiate into every cell type present in the body.Directed differentiation into motor neurons has been described for pluripotent cells.Although neurotrophic factors promote neuronal survival, their role in neuronal commitment is elusive.Here, we developed double-transgenic lines of mouse

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Inequities in utilization of maternal health interventions in Namibia: implications for progress towards MDG 5 targets

Abstract Background Inequities in the utilization of maternal health services impede progress towards the MDG 5 target of reducing the maternal mortality ratio by three quarters, between 1990 and 2015.In Namibia, despite increasing investments in the health sector, the maternal mortality ratio has increased from 271 per 100,000 live births in the p

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